Insulin Like Growth Factor (IGF)-1 (4-70), otherwise known as IGF-1 DES, produced in E. coli, is a single non-glycosylated, polypeptide chain containing 67 amino acids and having a molecular mass of 7,372 Da. In vitro studies demonstrate that at equal doses DES (1-3) IGF is ten times more potent than IGF-1 at stimulating hypertrophy and proliferation in cultured cells. It is likely generated through post-translational modification in the sequence of circulating mature IGF-1 via protease action. IGF-1 DES is a cleaved form of IGF-1 and contains amino acids 4-70. This structure has allowed the effects of the IGF-1 protein to be amplified in the more stable form of the DES 1,3 molecule peptide protein fragment of Insulin-like growth factor 1. The IGF-1 DES, or insulin-like growth factor DES, comes from the IGF-1 family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone and IGF-1 DES, although shorter, pacts an equal amount of physiological altering protein physical changes. Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed ‘sulfation factor,’ which later became known as ‘somatomedin’ or IGF-1 and more recently through truncation, DES IGF-1.

What is IGF-1 DES?

IGF1-DES is an insulin related or insulin analog what the body naturally makes. It effects the hormone system, mostly in the liver, and regulates energy and fat loss. IGF1-DES also spurs cell production and can help with anti-aging or tissue damage. IGF-1 DES is more powerful than the IGF-1 and its counterpart. It means that even though the chain for IGF-1 DES has a duration period of 20-30 minutes, it can give larger benefits in the long term run. Which means that IGF-1 DES should be administered in the muscles you want to see transform and change overtime using IGF-1 DES. IGF-1 DES can stimulate tissue growth during training by attaching to the lactic acid being formed by the muscles. Hence why IGF-1 DES can be used much longer than IGF-1 counterparts.

How much IGF-1 DES should I take?

A typical protocol would be: 50-150mcg multiple times a day of IGF-1 DES into the localized region you want to see growth.

Example, if you want to administer 150mcg of IGF-1 DES into the thigh, then you inject directly into the area.

The typical protocol for injection should be: Administration should be given prior to training into specific target areas.

What are the side effects of IGF-1 DES?

IGF1-DES can increase tumor size in patients who already have cancer. It does not affect anyone who does not have cancer, but can cause tumors to develop after long term use. Hypoglycemia is easy to happen with IGF1-DES due to miscalculation of the dosage or over dosage of the drug itself. Do not use this for headaches, as it can be abused quite easily.

IGF1-DES can increase tumor size in patients who already have cancer. It does not affect anyone who does not have cancer, but can cause tumors to develop after long term use. Hypoglycemia is easy to happen with IGF1-DES due to miscalculation of the dosage or over dosage of the drug itself. Do not use this for headaches, as it can be abused quite easily.

Some positive side effects of IGF1-DES include: regulating fat for use as energy, which can result in fat loss, anti-aging contributions by slowing down aging and boosting cell reduction in the process. Low levels of IGF-1 are linked to heart failure, lower brain cell regulation and neuron function as well as muscle tissue breakdown. So IGF1-DES can help regulate those problem areas, increases nutrient shuttling (aka protein synthesis), increased regenerative functions of nerve tissues and the ability to cause hyperplasia in muscle cells resulting in fuller muscle tissue.

How long should I store IGF-1 DES?

To store IGF1-DES you can store it as a liquid or as a powder in a cool area of the house. If you store it in the fridge, you will have to warm it up to room temperature prior to use